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Inhibition of MMP-1 expression by antisense RNA decreases invasiveness of human chondrosarcoma

โœ Scribed by Xiaoling Jiang; Charyl M Dutton; Wen-ning Qi; Joel A Block; Pnina Brodt; Margaret Durko; Sean P Scully


Book ID
108457064
Publisher
Elsevier Science
Year
2003
Tongue
English
Weight
798 KB
Volume
21
Category
Article
ISSN
0736-0266

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## Abstract Matrix metalloproteinases (MMPs) play a crucial role in tumor cell invasion and metastasis. Expression of MMPโ€1 has been reported as a prognostic predictor of recurrence in human chondrosarcoma, and studies using human chondrosarcoma cell lines indicate that MMPโ€1 expression levels corr