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Inhibition of MG132-induced mitochondrial dysfunction and cell death in PC12 cells by 3-morpholinosydnonimine

โœ Scribed by Chung Soo Lee; Eun Sook Han; Eon Sob Park; Hyoweon Bang


Book ID
113500337
Publisher
Elsevier Science
Year
2005
Tongue
English
Weight
464 KB
Volume
1036
Category
Article
ISSN
0006-8993

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Proteasomal dysfunction has been implicated in neurodegenerative disorders and during aging processes. In frontotemporal dementias, corticobasal degeneration, and progressive supranuclear palsy, oligodendrocytes are specifically damaged. Application of proteasomal inhibitors to cultured oligodendroc