Inhibition of Methionine Biosynthesis in Botrytis cinerea by the Anilinopyrimidine Fungicide Pyrimethanil
✍ Scribed by Fritz, Rene; Lanen, Catherine; Colas, Virginie; Leroux, Pierre
- Publisher
- John Wiley and Sons
- Year
- 1997
- Tongue
- English
- Weight
- 278 KB
- Volume
- 49
- Category
- Article
- ISSN
- 1526-498X
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✦ Synopsis
When mycelium of Botrytis cinerea was treated with low concentrations of the anilinopyrimidine fungicide pyrimethanil the total amount of free amino acids increased. Qualitative variations were also induced : alanine, glutamine, lysine, glycine, histidine, asparagine, arginine, threonine and moreover, aaminobutyrate and b-alanine were accumulated ; cyst(e)ine, valine, leucine and citrulline were reduced. When mycelium of B. cinerea was incubated with pyrimethanil at 1É5 kM induced a decrease of [35S]methionine and Na 2
[35S]O 4 , simultaneously an increase of [35S]cystathionine. These data indicate that the anilinopyrimidine fungicide pyrimethanil inhibits the biosynthesis of methionine and suggest that the primary target could be the cystathionine b-lyase.