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Inhibition of metastasis by a dialysable factor in fetal bovine serum in B16 melanoma cells

✍ Scribed by Takahide Ota; Masayo Maeda; Takeshi Matsui; Hiroyuki Kohno; Mikio Tanino; Shizuo Odashima

Book ID
117468382
Publisher
Elsevier Science
Year
1996
Tongue
English
Weight
406 KB
Volume
110
Category
Article
ISSN
0304-3835

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A cytosolic sialidase cDNA was transfected into a highly metastatic and invasive cell line, B16-BL6, derived from the murine B16 melanoma. Stable transfection of a cytosolic sialidase expression vector yielded 4 transfectants with high content of the exogenous sialidase protein as well as enzyme act