Overexpression of basic fibroblast growt
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Robert Wieder; Eyal Fenig; Huisheng Wang; Qin Wang; Shoshana Paglin; Thomas Menz
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Article
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1998
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John Wiley and Sons
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English
โ 606 KB
Basic fibroblast growth factor (bFGF, FGF-2) is progressively lost from mammary epithelial cells as they become malignant. To investigate the effects of restoring the expression of bFGF in breast cancer cells, we constructed MCF-7 cells that permanently overexpress 18-kD cytoplasm-localizing bFGF (M