Inhibition of mammary gland cyclic AMP-dependent protein kinase by arginine-rich histones
โ Scribed by J.L. Bear; J.G. Zalitis; A.G. Mackinlay
- Book ID
- 118312212
- Publisher
- Elsevier Science
- Year
- 1978
- Tongue
- English
- Weight
- 409 KB
- Volume
- 84
- Category
- Article
- ISSN
- 0006-291X
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๐ SIMILAR VOLUMES
Extracts of fasted rat diaphragms, previously treated with or without insulin were assayed for glycogen synthase, protein kinase and cyclic [3H]-AMP binding. Treatment with insulin produced an elevation in the % of glycogen synthase I and a concurrent decrease in cyclic AMP-dependent protein kinase
Limited proteolysis of catalytic and regulatory subunits of cyclic AMP-dependent protein kinase (A-pk), cyclic AMP phosphodiesterase, glycogen synthase, and histones by fungal protease (type XIX) was analyzed by the digested peptide bands in SDS polyacrylamide gel electrophoresis. The modulatory eff