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Inhibition of lymphocyte adhesion to cytokine-activated synovial fibroblasts by glucocorticoids involves the attenuation of vascular cell adhesion molecule 1 and intercellular adhesion molecule 1 gene expression

✍ Scribed by Philippe A. Tessier; Paola Cattaruzzi; Shaun R. McColl


Publisher
John Wiley and Sons
Year
1996
Tongue
English
Weight
819 KB
Volume
39
Category
Article
ISSN
0004-3591

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## Abstract ## Objective To investigate the roles of MAPKs and NF‐κB in tumor necrosis factor α (TNFα)–induced expression of vascular cell adhesion molecule 1 (VCAM‐1) in human rheumatoid arthritis synovial fibroblasts (RASFs). ## Methods Human RASFs were isolated from synovial tissue obtained f