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Inhibition of lipopolysaccharide-mediated human monocyte activation, in vitro, by α1-antitrypsin

✍ Scribed by Sabina Janciauskiene; Susanne Larsson; Peter Larsson; Robert Virtala; Lennart Jansson; Tim Stevens


Book ID
116288851
Publisher
Elsevier Science
Year
2004
Tongue
English
Weight
523 KB
Volume
321
Category
Article
ISSN
0006-291X

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Background: α1-antitrypsin (AAT) is one of the major serine proteinase inhibitors controlling proteinases in many biological pathways. There is increasing evidence that AAT is able to exert other than antiproteolytic effects. To further examine this question we compared how various doses of the nati