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Inhibition of leucotriene-synthesis improves dorsal skin flap survival in the rat

✍ Scribed by TÖRKVIST, L. ;ÅDÉN, U. ;LUNDEBERG, T. ;RAUD, J.

Book ID
114870829
Publisher
John Wiley and Sons
Year
1995
Tongue
English
Weight
145 KB
Volume
154
Category
Article
ISSN
0001-6772

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Nitric oxide synthase inhibitors improve
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## Abstract The ability of nitric oxide (NO) synthase inhibitors to reduce ischemia‐induced skin flap necrosis was assessed using a modified McFarlane flap in the rat. Flap survival was significantly improved in L‐NIO treated (86 ± 2%), L‐NAME‐treated (84 ± 2%), and aminoguanidine‐treated (76 ± 2%)