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Inhibition of Ku heterodimer DNA end binding activity during granulocytic differentiation of human promyelocytic cell lines

✍ Scribed by Muller, Catherine; Monferran, Sylvie; Gamp, Alexander-Christopher; Calsou, Patrick; Salles, Bernard


Book ID
110064834
Publisher
Nature Publishing Group
Year
2001
Tongue
English
Weight
352 KB
Volume
20
Category
Article
ISSN
0950-9232

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## Abstract Amplification of __MYCN__ is one of the most important prognostic markers for neuroblastoma and is correlated with rapid tumor progression and poor prognosis. MYCN belongs to the Myc/Max/Mad/Mnt network of proteins that regulate proliferation, apoptosis, and differentiation. It is well