## Abstract Efforts have been made to develop a chemoprevention strategy that selectively triggers apoptosis in malignant cancer cells. Previous studies showed that capsaicin, the major pungent ingredient of red pepper, had differential effect between normal and transformed cells. As an approach to
Inhibition of Invasion and Induction of apoptosis by curcumin in H-ras-Transformed MCF10A human breast epithelial cells
โ Scribed by Mi-Sung Kim; Hye-Jung Kang; Aree Moon
- Publisher
- Springer
- Year
- 2001
- Tongue
- English
- Weight
- 906 KB
- Volume
- 24
- Category
- Article
- ISSN
- 0253-6269
No coin nor oath required. For personal study only.
๐ SIMILAR VOLUMES
Although Src transformation of NIH3T3 mouse fibroblasts has been shown to be dependent on Ras function, the signaling mechanism whereby Src induces malignant transformation of human epithelial cells still remains unclear. In the present study, we analyzed the functional role of Ras, which acts downs
## Abstract There is significant evidence that the __ras__ oncogene plays a role in experimental mammary carcinogenesis; the evidence in human breast cancer, however, is more limited. We induced the expression of transformation phenotypes in the human breast epithelial cell line MCFโ10F with the ch