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Inhibition of interleukin-8-activated human neutrophil chemotaxis by thapsigargin in a calcium-and cyclic AMP-dependent way

✍ Scribed by Jan G.R Elferink; Ben M de Koster


Book ID
113994672
Publisher
Elsevier Science
Year
2000
Tongue
English
Weight
281 KB
Volume
59
Category
Article
ISSN
0006-2952

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## Abstract CXCL8 is a CXC chemokine that recruits leukocytes to sites of inflammation. Expression of CXCL8 in the CNS has been demonstrated in neuroinflammatory diseases, including human immunodeficiency virus (HIV‐1) encephalitis, but the mechanism of secretion of this chemokine is not fully unde