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Inhibition of Interleukin-3-Dependent Growth of CD34+ Acute Myelogenous Leukemia Cells by Recombinant Soluble CD23

โœ Scribed by M. DJAVAD MOSSALAYI; HELENE MERLE-BERAL; ALI H. DALLOUL; MICHEL AROCK; ARIANE MICHEL; HANS HOFSTETTER; PATRICE DEBRE


Book ID
119865615
Publisher
John Wiley and Sons
Year
1991
Tongue
English
Weight
259 KB
Volume
628
Category
Article
ISSN
0890-6564

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We have studied the interaction of 35S-labeled recombinant IL-3 with the acute myelogenous leukemia cell line, KG-1. 35S-IL-3 bound to these cells in a time dependent, saturable, and specific manner at 4OC. Scatchard transformation of binding isotherms demonstrated the existence of a small number (2