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Inhibition of insulin release from the rat pancreas by cyproheptadine and tricyclic antidepressants

โœ Scribed by H. G. Joost; W. Poser; U. Panten


Book ID
112342701
Publisher
Springer-Verlag
Year
1974
Tongue
English
Weight
235 KB
Volume
285
Category
Article
ISSN
0028-1298

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Inhibition of insulin production by cypr
โœ Miller, C. P. ;Reape, T. J. ;Fischer, L. J. ๐Ÿ“‚ Article ๐Ÿ“… 1993 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 733 KB

## ABSTRACE The clonal insulin producing cell line RINm5F was evaluated as a model for the action of cyproheptadine (CPH)-like diabetogenic compounds in the rat pancreas. Treatment with 10 & l CPH and selected structural analogs under culture conditions produced a progressive loss of cellular insu