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Inhibition of insulin-like growth factor I receptor tyrosine kinase by ethanol

โœ Scribed by Raphael Rubin; Rob Harrison; Xian-Feng Chen; Joseph Corzitotto; Jan B. Hoek; Hazem Hallak


Book ID
113487313
Publisher
Elsevier Science
Year
2004
Tongue
English
Weight
379 KB
Volume
68
Category
Article
ISSN
0006-2952

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## Abstract We studied expression and functional characteristics of the insulinโ€ and insulinโ€likeโ€growthโ€factorโ€1(IGFโ€1) receptors in human renal carcinoma. Ligandโ€binding properties and tyrosineโ€kinase activity of both receptors, as well as the expression of the 2 isoforms of the human insulin rec