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Inhibition of inflammatory CD4 T cell activity by murine liver sinusoidal endothelial cells

✍ Scribed by Carambia, Antonella; Frenzel, Christian; Bruns, Oliver T.; Schwinge, Dorothee; Reimer, Rudolph; Hohenberg, Heinrich; Huber, Samuel; Tiegs, Gisa; Schramm, Christoph; Lohse, Ansgar W.; Herkel, Johannes

Book ID
122954945
Publisher
Elsevier Science
Year
2013
Tongue
English
Weight
949 KB
Volume
58
Category
Article
ISSN
0168-8278

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CD4 Ψ‰ CD25 Ψ‰ regulatory T cells (Treg) are important mediators of peripheral immune tolerance; however, whether Treg participate also in hepatic immune tolerance is not clear. Therefore, we tested the potential of Treg to suppress stimulation of CD4 Ψ‰ T cells by liver sinusoidal endothelial cells (L