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Inhibition of inducible nitric oxide synthase (iNOS) and induction of heme oxygenase-1 by bismuth preparations in human intestinal epithelial cells

✍ Scribed by Cavicchi, Maryan; Gibbs, Linda; Whittle, Brendan J.

Book ID
122043363
Publisher
Elsevier Science
Year
2000
Tongue
English
Weight
174 KB
Volume
118
Category
Article
ISSN
0016-5085

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To determine whether heme oxygenase-1 (HO-1) protein is induced by endogenous nitric oxide (NO) in rat glial cultures, we examined the effects of lipopolysaccharide (LPS), interferon-β₯ (IFN-β₯), and NO donors such as S-nitroso-N-acetylpenicillamine (SNAP), in mixed glial cells and in vivo rat hippoca