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Inhibition of indoleamine 2,3-dioxygenase enhances the T-cell response to influenza virus infection

✍ Scribed by Fox, J. M.; Sage, L. K.; Huang, L.; Barber, J.; Klonowski, K. D.; Mellor, A. L.; Tompkins, S. M.; Tripp, R. A.


Book ID
124169601
Publisher
Society for General Microbiology
Year
2013
Tongue
English
Weight
820 KB
Volume
94
Category
Article
ISSN
0022-1317

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## Abstract ## Background Indoleamine 2,3‐dioxygenase (IDO) is an enzyme involved in the catabolism of tryptophan and has been shown to prevent rejection of the fetus during pregnancy by inhibiting alloreactive T cells. ## Methods In this study we investigated dendritic cells (DCs) that are tran