✦ LIBER ✦

Inhibition of in vivo tumorigenicity and invasiveness of a human glioblastoma cell line transfected with antisense uPAR vectors

✍ Scribed by Yoshinori Go; Shravan K. Chintala; Sanjeeva Mohanam; Ziya Gokaslan; Boyapati Venkaiah; Rolf Bjerkvig; Kazunari Oka; Garth L. Nicolson; Raymond Sawaya; Jasti S. Rao

Book ID: 110370059
Publisher: Springer
Year: 1997
Tongue: English
Weight: 730 KB
Volume: 15
Category: Article
ISSN: 0262-0898
DOI: 10.1023/a:1018410523635

No coin nor oath required. For personal study only.

📜 SIMILAR VOLUMES

In vitro inhibition of human glioblastom

In vitro inhibition of human glioblastoma cell line invasiveness by antisense uPA receptor

✍ Mohanam, Sanjeeva; Chintala, Shravan K; Go, Yoshinori; Bhattacharya, Anuradha; V 📂 Article 📅 1997 🏛 Nature Publishing Group 🌐 English ⚖ 712 KB

Partial suppression of tumorigenicity in

Partial suppression of tumorigenicity in a human lung cancer cell line transfected with Krev-1

✍ Jorge Caamano; Marion Dirado; Toshihiko Lizasa; Shigeru Momiki; Elma Fernandes; 📂 Article 📅 1992 🏛 John Wiley and Sons 🌐 English ⚖ 853 KB

## Abstract A human non‐small‐cell lung carcinoma cell line, Calu‐6 (from an anaplastic carcinoma), was transfected with the Ki‐__ras__‐related anti‐oncogene K__rev__‐1. Several transfectant lines were obtained that showed a reduced tumorigenicity in nude mice with respect to the parental and contr

Antisense inhibition of urokinase: Effec

Antisense inhibition of urokinase: Effect on malignancy in a human osteosarcoma cell line

✍ Carsten Haeckel; Sabine Krueger; Albert Roessner 📂 Article 📅 1998 🏛 John Wiley and Sons 🌐 French ⚖ 251 KB 👁 2 views

Expression of urokinase-type plasminogen activator (u-PA) strongly correlates with a malignant tumor cell phenotype. In the multistep process of metastasis, different cellular functions are influenced by urokinase. The enzyme is known to be effective via both proteolytical and signal transduction me

Inhibition of metastasis to lung of a hu

Inhibition of metastasis to lung of a human nasopharyngeal carcinoma cell line CNE- 2L2 transfected with pRc/ CMV-antisense 6A8 cDNA in nude mice

✍ Lixin Zhang; Yuqin Liu; Fengrong Ma; Pei Gu; Gengxian Shi; Xuemei Zhao; Bo Li; J 📂 Article 📅 1999 🏛 Science in China Press (SCP) 🌐 English ⚖ 580 KB

In vitro and in vivo accelertration of t

In vitro and in vivo accelertration of the neoplastic phenotype of a low-tumorigenicity rat bladder carcinoma cell line by transfected transforming growth factor-α

✍ Hitoshi Kawamata; Shuji Kameyama; Ryoichi Oyasu 📂 Article 📅 1994 🏛 John Wiley and Sons 🌐 English ⚖ 853 KB

## Abstract We conducted an experiment to determine whether expression of transforming growth factor‐α (TGF‐α) enhances tumorigenicity in a low‐tumorigenicity rat bladder carcinoma cell line and whether it is sufficient to induce a tumorigenic phenotype in a nontumorigenic rat bladder cell line. D4

Co-expression of urokinase-type plasmino

Co-expression of urokinase-type plasminogen activator and its receptor in human gastric-cancer cell lines correlates with their invasiveness and tumorigenicity

✍ Il-Kyoo Park; Bum-Joon Kim; Young-Joo Goh; Mi-Ae Lyu; Chung-Gyu Park; Eung-Soo H 📂 Article 📅 1997 🏛 John Wiley and Sons 🌐 French ⚖ 205 KB 👁 1 views

The expression of urokinase-type plasminogen activator (u-PA), its receptor (u-PAR) and metalloproteases activity were analyzed in 4 human gastric-cancer cell lines (AGS, Hs746T, SNU-1, and SNU-5), in an attempt to relate these activities to their invasive potential and tumorigenicity on the modifie