✦ LIBER ✦

Inhibition of in vitroimmunoglobulin production by IL-12 in murine chronic graft- vs. -host disease: synergism with IL-18

✍ Scribed by Bernard R. Lauwerys; Jean-Christophe Renauld; Frédéric A. Houssiau

Publisher: John Wiley and Sons
Year: 1998
Tongue: English
Weight: 135 KB
Volume: 28
Category: Article
ISSN: 0014-2980
DOI: 10.1002/(sici)1521-4141(199806)28:06<2017::aid-immu2017>3.0.co;2-2

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✦ Synopsis

We investigated the effects of IL-12 on immunoglobulin (Ig) production in vitro in murine chronic graft-vs.-host disease (cGVHD), a lupus-like model of overt B cell activation induced by allogeneic stimulation.