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Inhibition of in vitro protein synthesis in a rabbit reticulocyte cell-free system by toxic trypsic peptides from ricin

โœ Scribed by Lugnier, Alain A.J.; Le Meur, Marie Anne; Gerlinger, Pierre; Dirheimer, Guy


Book ID
121985619
Publisher
Elsevier Science
Year
1974
Tongue
English
Weight
185 KB
Volume
56
Category
Article
ISSN
0300-9084

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A variety of methylated 4-oxypiperidine derivatives were tested for their ability to inhibit protein synthesis in vitro. A direct correlation was found between the extent of methylation of these compounds and their inhibitory activity in a rabbit reticulocyte lysate cell-free translation system.