Inhibition of in vitro proliferative response of cultured t lymphocytes to interleukin-2 by gold sodium thiomalate

Interleukin 2 counteracts the inhibition

Interleukin 2 counteracts the inhibition of cytotoxic T lymphocytes by cholera toxin in vitro and in vivo

✍ Miriam Moscovitch-Lopatin; Raymond J. Petrillo; O. G. Pankewycz; Edward Hadro; C 📂 Article 📅 1991 🏛 John Wiley and Sons 🌐 English ⚖ 661 KB

## Abstract Cholera toxin irreversibly activates a 43‐kDa guanosine triphosphate (GTP)‐binding protein by adenosine diphosphate ribosylation, resulting in activation of adenylate cyclase and increased intracellular levels of cyclic adenosine monophosphate (cAMP). Because increases in intracellular