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Inhibition of human vascular smooth muscle cell proliferation by lovastatin: the role of isoprenoid intermediates of cholesterol synthesis

✍ Scribed by E. MUNRO; M. PATEL; P. CHAN; L. BETTERIDGE; G. CLUNN; K. GALLAGHER; A. HUGHES; M. SCHACHTER; J. WOLFE; P. SEVER

Book ID
114727307
Publisher
John Wiley and Sons
Year
1994
Tongue
English
Weight
704 KB
Volume
24
Category
Article
ISSN
0014-2972

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The proliferation of vascular smooth muscle cells (VSMC) was stimulated by co-incubation with macrophages. Further stimulation was observed when co-incubated macrophages were supplied with LDL or cholesterol. However, the stimulation of VSMC proliferation did not result from co-incubation with macro