Inhibition of human osteoblast marker gene expression by retinoids is mediated in part by insulin-like growth factor binding protein-6
β Scribed by Tao Yan; Jon Wergedal; Yuehua Zhou; Subburaman Mohan; David J Baylink; Donna D Strong
- Book ID
- 117837117
- Publisher
- Elsevier Science
- Year
- 2001
- Tongue
- English
- Weight
- 228 KB
- Volume
- 11
- Category
- Article
- ISSN
- 1096-6374
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Insulin-like growth factor-I (IGF-I) is essential for normal epidermal homeostasis; however, the role of IGF binding proteins (IGFBPs), regulators of IGF action, remains unclear. Here we examine the regulation of human keratinocyte-produced IGFBPs by epidermal growth factor (EGF), transforming growt