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Inhibition of human lymphocyte activation by wheat germ agglutinin: A model for saccharide-specific suppressor factors

โœ Scribed by Douglas J. Barrett; John R. Edwards; Biagio A. Pietrantuono; Elia M. Ayoub


Book ID
113132657
Publisher
Elsevier Science
Year
1983
Tongue
English
Weight
749 KB
Volume
81
Category
Article
ISSN
0008-8749

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The effect of plant lectins on amino acid uptake and DNA synthesis in cultured human skin fibroblasts stimulated by various peptide mitogens was studied. Wheat germ agglutinin (WGA), at a concentration of 5 micrograms/ml, which by itself had little effect on 3H-aminoisobutyric acid (AIB) uptake, mar