Inhibition of human group II phospholipase A2 by C-reactive protein in vitro
β Scribed by Peter Vadas; Eva Stefanski; Brigitte Grouix; B.Diana Schouten; Waldemar Pruzanski
- Book ID
- 118415036
- Publisher
- Elsevier Science
- Year
- 1995
- Tongue
- English
- Weight
- 993 KB
- Volume
- 11
- Category
- Article
- ISSN
- 0929-7855
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π SIMILAR VOLUMES
Melittin and phospholipase A 2 -activating protein (PLAP) are known as efficient activators of secretory phospholipase A 2 (sPLA 2 ) types I, II, and III when phospholipid liposomes are used as substrate. The present study demonstrates that both peptides can either inhibit or activate sPLA 2 dependi
To establish the dose dependency of phospholipase A 2 (PLA 2 ) inhibition by the organophosphorus compound (OPC) paraoxon (POX), human platelet membranes were incubated after Ca 2+ removal (to inactivate the PLA 2 ) with 0.3, 1 and 3 g ml Ψ1 POX for 5, 30 and 60 min each. The PLA 2 activity (pmol mg