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Inhibition of human allergic T-cell responses by IL-10–treated dendritic cells: Differences from hydrocortisone-treated dendritic cells

✍ Scribed by Bellinghausen, Iris; Brand, Udo; Steinbrink, Kerstin; Enk, Alexander H.; Knop, Jürgen; Saloga, Joachim

Book ID: 119765355
Publisher: Elsevier Science
Year: 2001
Tongue: English
Weight: 182 KB
Volume: 108
Category: Article
ISSN: 1097-6825
DOI: 10.1067/mai.2001.117177

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## Abstract We have previously shown that human monocyte‐derived dendritic cells (DC) express indoleamine 2,3‐dioxygenase (IDO), as well as several other enzymes of the kynurenine pathway at the mRNA level upon maturation. The tolerogenic mechanisms of this pathway remain unclear. Here we show that