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Inhibition of hormone-dependent and independent breast cancer cell growthin vivoandin vitrowith the antiestrogen toremifene and recombinant human interferon-α2

✍ Scribed by Simon P. Robinson; David Goldstein; Patricia L. Witt; Ernest C. Borden; V. Craig Jordan

Publisher
Springer US
Year
1990
Tongue
English
Weight
562 KB
Volume
15
Category
Article
ISSN
0167-6806

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Recombinant human leukocyte interferon-α 2b stimulates the synthesis and release of a 90k tumor-associated antigen in human breast cancer cells
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We have previously reported the production of a new monoclonal antibody (MAb) (SP-2) recognizing a 90-kDa tumorassociated antigen, termed 9OK. which is increased in the serum of many cancer patients. Treatment of CG5 human breast cancer cells with recombinant interferon-a 2b (rlFN-a 2b) can increase