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Inhibition of HIV-1 IIIb replication in AA-2 and NT-2 cells in culture by two ligands of poly (ADP-ribose) polymerase: 6-amino-1,2-benzopyrone and 5-iodo-6-amino-1,2-benzopyrone

✍ Scribed by Gerald A. Cole; Gerhard Bauer; Eva Kirsten; Jerome Mendeleyev; Pal I. Bauer; Kalman G. Buki; Alaeddin Hakam; Ernest Kun


Book ID
117055327
Publisher
Elsevier Science
Year
1991
Tongue
English
Weight
598 KB
Volume
180
Category
Article
ISSN
0006-291X

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✍ Liju Fan; Elizabeth G. Snyderwine 📂 Article 📅 1994 🏛 John Wiley and Sons 🌐 English ⚖ 667 KB

## Abstract 2‐Amino‐3‐methylimidazo[4,5‐f]quinoline (IQ) and 2‐amino‐1‐methyl‐6‐phenylimidazo[4,5‐__b__)]pyridine (PhIP) are two members of a family of carcinogenic heterocyclic amines (HAs) found in cooked meats that form DNA adducts after activation to __N__‐acetoxy derivatives. The ability of IQ