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Inhibition of histone deacetylation by trichostatin A intensifies the transcriptions of neuronal c-fos and c-jun genes after kainate stimulation

✍ Scribed by Judy Chia Ghee Sng; Hideo Taniura; Yukio Yoneda

Book ID
116767914
Publisher
Elsevier Science
Year
2005
Tongue
English
Weight
413 KB
Volume
386
Category
Article
ISSN
0304-3940

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## Abstract The AICD (APP intracellular Domain) and C31, caspase‐cleaved C‐terminal fragment of APP, have been found in Alzheimer's disease (AD) patients' brains and have been reported to induce apoptosis in neuronal cells. In recent, the C‐terminal fragments of amyloid precursor protein (APP‐CTs)