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Inhibition of heregulin mediated MCF-7 breast cancer cell growth by the ErbB3 binding protein EBP1

โœ Scribed by Yuexing Zhang; Damilola Akinmade; Anne W. Hamburger

Book ID
116334698
Publisher
Elsevier Science
Year
2008
Tongue
English
Weight
219 KB
Volume
265
Category
Article
ISSN
0304-3835

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Ebp1, an ErbB-3 binding protein, translocates from the cytoplasm to the nucleus of human breast cancer cells after treatment with the ErbB-3 ligand, heregulin. The purpose of these studies was to examine the effects of ectopic expression of ebp1 on the biological properties of human ErbB-3-expressin