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Inhibition of hepatitis C virus replication through adenosine monophosphate-activated protein kinase-dependent and -independent pathways

✍ Scribed by Kenji Nakashima; Kenji Takeuchi; Kazuyasu Chihara; Hak Hotta; Kiyonao Sada


Book ID
108578573
Publisher
Center for Academic Publications, Japan
Year
2011
Tongue
English
Weight
321 KB
Volume
55
Category
Article
ISSN
0385-5600

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A method is described that enabled us to study the adhesiveness of J-774 murine macrophages. Cell attachment was stimulated by activators of kinase C (i.e., phorbol esters) as well as kinase A (cyclic adenosine monophosphate; cAMP). This novel effect of cAMP was observed when its levels were increas