Inhibition of hepatic mitochondrial aldehyde dehydrogenase by carbon tetrachloride through JNK-mediated phosphorylation
β Scribed by Kwan-Hoon Moon; Young-Mi Lee; Byoung-Joon Song
- Book ID
- 113631034
- Publisher
- Elsevier Science
- Year
- 2010
- Tongue
- English
- Weight
- 946 KB
- Volume
- 48
- Category
- Article
- ISSN
- 0891-5849
No coin nor oath required. For personal study only.
π SIMILAR VOLUMES
The hepatic oxidation of ethanol has been demonstrated to cause peroxidation of cellular membranes, resulting in the production of aldehydes that are substrates for hepatic aldehyde dehydrogenases. It was the purpose of this study to evaluate the cooxidation of the lipid peroxidation product, truns-
The inhibition of rat hepatic mitochondria1 aldehyde dehydrogenase (ALDH) isozymes was studied in apparent steady-state conditions after repeated intra-peritoneal cyanamide administration. The low-K, mitochondria1 ALDH isozyme was more susceptible to cyanamide-induced inhibition (DIs0 = 0.104 mg kgl