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Inhibition of Helicobacter pylori Urease by Phenyl Phosphorodiamidates: Mechanism of Action

✍ Scribed by W.Stephen Faraci; Bingwei V. Yang; Dawn O'Rourke; Robin W. Spencer


Book ID
103992105
Publisher
Elsevier Science
Year
1995
Tongue
English
Weight
425 KB
Volume
3
Category
Article
ISSN
0968-0896

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Macromolecular assembly of Helicobacter
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## Abstract The supramolecular assembly of __Helicobacter pylori__ urease was studied by nanoflow electrospray ionization orthogonal time‐of‐flight mass spectrometry. The measured molecular mass of the urease complex of 1.06 MDa corresponds to a dodecameric (Ξ±Ξ²)~12~ assembly of urease Ξ± (26 kDa) an