Inhibition of granulocyte-macrophage (GM) colony formation by basic polypeptides from mouse Ehrlich ascites tumor cells

Growth regulation of the AML-193 leukemi

Growth regulation of the AML-193 leukemic cell line: Evidence for autocrine production of granulocyte-macrophage colony-stimulating factor (GM-CSF), and inhibition of GM-CSF-dependent cell proliferation by interleukin-1 (IL-1) and tumor necrosis factor (tnfα)

✍ Vincent Kindler; John Shields; Dominique Ayer; Gonzalo J. Mazzei 📂 Article 📅 1991 🏛 John Wiley and Sons 🌐 French ⚖ 583 KB

The human leukemic cell line AML-193 was tested for its proliferative response to endogenously produced autocrine factors and to a variety of cytokines and colony-stimulating factors. Cells grown in the absence of GM-CSF incorporated tritiated thymidine, and this was partially reversed by adding neu