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Inhibition of glycoprotein secretion by ethanol and acetaldehyde in rat liver slices

✍ Scribed by Dean J. Tuma; Rowen K. Zetterman; Michael F. Sorrell

Book ID
115775108
Publisher
Elsevier Science
Year
1980
Tongue
English
Weight
577 KB
Volume
29
Category
Article
ISSN
0006-2952

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Ethanol administration inhibits hepatic protein and glycoprotein secretion. Previous studies have shown that the metabolism of ethanol is required for this effect. Experiments were designed to determine whether acetaldehyde, the first metabolite of ethanol oxidation, mediated the ethanol-induced sec