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Inhibition of Glucocorticoid-Induced Apoptosis with 5-Aminoimidazole-4-carboxamide Ribonucleoside, a Cell-Permeable Activator of AMP-Activated Protein Kinase

✍ Scribed by Claudio Stefanelli; Ivana Stanic’; Francesca Bonavita; Flavio Flamigni; Carla Pignatti; Carlo Guarnieri; Claudio M. Caldarera


Book ID
115581662
Publisher
Elsevier Science
Year
1998
Tongue
English
Weight
388 KB
Volume
243
Category
Article
ISSN
0006-291X

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✍ Chih-Lin Kuo; Feng-Ming Ho; Mei Ying Chang; Ekambaranellore Prakash; Wan-Wan Lin 📂 Article 📅 2008 🏛 John Wiley and Sons 🌐 English ⚖ 311 KB

## Abstract Recent studies suggest AMP‐activated protein kinase (AMPK), an enzyme involved in energy homeostasis, might be a novel signaling pathway in regulating inflammatory response, but the precise intracellular mechanisms are not fully understood. In this study, we have demonstrated that 5‐ami