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Inhibition of ganglioside synthesis abrogrates neuroblastoma mediated lymphocyte apoptosis

✍ Scribed by E.M. Barksdale Jr; G.V. Shurin; M.T. Lotze


Book ID
114124390
Publisher
Elsevier Science
Year
1999
Tongue
English
Weight
76 KB
Volume
56
Category
Article
ISSN
0149-7944

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## Background: Neurotrophins mediate their effects by binding to members of the trk family of receptor tyrosine kinases and to the low-affinity nerve growth factor receptor p75. nerve growth factor (ngf) has been demonstrated to support survival and differentiation of neuroblastoma (nb) cells by ac