## Abstract Transforming growth factor ฮฒ1 (TGFฮฒ1) inhibits epithelial cell proliferation late in the G1 phase of the cell cycle. We examined the effect of TGFฮฒ1 on known late G1 cell cycle regulators in an attempt to determine the molecular mechanism of growth inhibition by this physiological inhib
โฆ LIBER โฆ
Inhibition of G1 Cyclin Expression and G1 Cyclin-Dependent Protein-Kinases by cAMP in an Astrocytic Cell Line
โ Scribed by C. Gagelin; M. Pierre; D. Torudelbauffe
- Book ID
- 115575779
- Publisher
- Elsevier Science
- Year
- 1994
- Tongue
- English
- Weight
- 447 KB
- Volume
- 205
- Category
- Article
- ISSN
- 0006-291X
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Progressive deregulation of the cell-division cycle is thought to contribute to the establishment and progression of neoplasia. Previously, we have documented the in vivo inactivation of p16 INK4A , an inhibitor of G 1 cyclin-dependent kinases, in squamous cell carcinomas of the head and neck region