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Inhibition of furin by serpin Spn4A from Drosophila melanogaster

✍ Scribed by Mareke Oley; Matthias C. Letzel; Hermann Ragg

Book ID
116464971
Publisher
Elsevier Science
Year
2004
Tongue
English
Weight
682 KB
Volume
577
Category
Article
ISSN
0014-5793

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An inibition study of the Ξ²-carbonic anhydrase (CA, EC 4.2.1.1) DmBCA from the insect Drosophila melanogaster with sulfonamides and sulfamates is reported. Among the panel of 40 investigated compounds, the best DmBCA inhibitors were the sulfonylated benzenesulfonamides and ethoxzolamide, which showe