𝔖 Bobbio Scriptorium
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Inhibition of folate-dependent enzymes by 7-OH-methotrexate

✍ Scribed by Pam W. Sholar; Jacob Baram; Richard Seither; Carmen J. Allegra


Book ID
115780678
Publisher
Elsevier Science
Year
1988
Tongue
English
Weight
598 KB
Volume
37
Category
Article
ISSN
0006-2952

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β€œInhibition” of the Enzyme Model TpPh,Me
✍ Teame Tekeste; Heinrich Vahrenkamp πŸ“‚ Article πŸ“… 2006 πŸ› John Wiley and Sons 🌐 English βš– 144 KB

## Abstract In order to gain a structural understanding of zinc enzyme inhibition, the model complex Tp^Ph,Me^Zn–OH was treated with various diketo compounds. α‐Keto carboxylic acids were attached to the zinc ion as anionic O,O‐chelate ligands, of which benzoylformate was oxidatively decarboxylated