## Abstract Deregulation of cell survival pathways and resistance to apoptosis are widely accepted to be fundamental aspects of tumorigenesis. As in many tumours, the aberrant growth and survival of colorectal tumour cells is dependent upon a small number of highly activated signalling pathways, th
โฆ LIBER โฆ
Inhibition of fatty acid synthase induces pro-survival Akt and ERK signaling in K-Ras-driven cancer cells
โ Scribed by Yellen, Paige; Foster, David A.
- Book ID
- 127107842
- Publisher
- Elsevier Science
- Year
- 2014
- Tongue
- English
- Weight
- 812 KB
- Volume
- 353
- Category
- Article
- ISSN
- 0304-3835
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## Abstract Garcinol, from the fruit rind of __Garcinia indica__ and other species, has been reported to suppress colonic aberrant crypt foci (ACF) formation in rats. In this study, we investigate the beneficial effects of tumor prevention by garcinol on the human colorectal cancer cell line, HTโ29