Inhibition of Fatal Anaphylaxis in Mice inoculated with a Virus-induced Leukaemic Tumour Extract

In vivo production of tumour necrosis fa

In vivo production of tumour necrosis factor-α and interleukin-6 in BALB/c mice inoculated intranasally with a high dose of respiratory syncytial virus

✍ P. J. Hayes; R. Scott; J. Wheeler 📂 Article 📅 1994 🏛 John Wiley and Sons 🌐 English ⚖ 716 KB

## Abstract Intranasal administration of an inoculum of 10^7^ focus‐forming units (FFU) of respiratory syncy‐tial (RS) virus induced disease in BALB/c mice with signs of anorexia, cachexia, ruffled fur, and pneumonia. Mice displayed mild signs of illness on day 1 postinoculation (PI), followed by a