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Inhibition of eukaryotic DNA-dependent RNA polymerase release from isolated nuclei and nucleoli by phenylmethylsulfonylfluoride

โœ Scribed by Thomas J. Lindell


Book ID
115702406
Publisher
Elsevier Science
Year
1975
Tongue
English
Weight
756 KB
Volume
171
Category
Article
ISSN
0003-9861

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For pharmacological and toxicological studies on the effect of drugs on transcriptional processes the basic fluctuation in activity during a 24-h period must be known. We have measured the activity of nuclear and mitochondrial DNA-dependent RNA polymerases in cell fractions from mice kept under defi