An efficient method to synthetically produce optically enriched (aR,bS)-epoxyketones was developed using a quaternary ammonium salt derived from cinchona alkaloid as the chiral phase-transfer catalyst. (aR,bS)-Epoxyketones were prepared in high optical purities (91-99% ee) by the asymmetric epoxidat
✦ LIBER ✦
Inhibition of epoxide metabolism by α,β-epoxyketones and isosteric analogs
✍ Scribed by Glenn D. Prestwich; Jing-Wen Kuo; Sang-Kyu Park; Dana N. Loury; Bruce D. Hammock
- Book ID
- 115706595
- Publisher
- Elsevier Science
- Year
- 1985
- Tongue
- English
- Weight
- 440 KB
- Volume
- 242
- Category
- Article
- ISSN
- 0003-9861
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