In mixed glial cell cultures from cerebral cortices of newborn rats, endotoxin induces inducible nitric oxide (iNOS), nitric oxide (NO), and interleukin-1 beta (IL-1 beta) production in microglial cells. Earlier we demonstrated that endotoxin induced iNOS but not IL-1 beta expression in microglial c
✦ LIBER ✦
Inhibition of DNA synthesis in cultured hepatocytes by endotoxin-conditioned medium of activated stellate cells is transforming growth factor-β and nitric oxide-independent
✍ Scribed by Tadahiro Uemura; Chandrashekhar R Gandhi
- Book ID
- 110005770
- Publisher
- Nature Publishing Group
- Year
- 2001
- Tongue
- English
- Weight
- 246 KB
- Volume
- 133
- Category
- Article
- ISSN
- 0007-1188
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## Abstract In a previous study, we revealed that tumor necrosis factor (TNF) was secreted in mouse liver at an early phase of liver regeneration after partial hepatectomy. Here, we investigated direct actions of TNF on the in vitro DNA synthesis of adult mouse hepatocytes in primary culture. TNF e