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Inhibition of DNA polymerase α activity by proteins from rat liver

✍ Scribed by Carolyn M. Klinge; Dai Kee Liu

Publisher: Elsevier Science
Year: 1985
Tongue: English
Weight: 634 KB
Volume: 17
Category: Article
ISSN: 0020-711X
DOI: 10.1016/0020-711x(85)90210-1

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## Abstract A nuclear DNA complex containing DNA polymerase and SV40 T‐antigen was isolated from nuclei of SV40‐transformed mouse fibroblasts. DNA polymerase could be separated from the complex. The remaining DNA/T‐antigen‐containing complex stimulated DNA polymerase a activity about 10‐fold. The c