๐”– Bobbio Scriptorium
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Inhibition of dihydrofolate reductase by dichloromethotrexate and its metabolite

โœ Scribed by D.K. Misra; R.H. Adamson; T.L. Loo; V.T. Oliverio

Book ID
118932977
Publisher
Elsevier Science
Year
1963
Tongue
English
Weight
123 KB
Volume
2
Category
Article
ISSN
0024-3205

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The ability of the enzyme dihydrofolate reductase to catalyze the formation of tetrahydrobiopterin from dihydrobiopterin was used to develop a method for measuring the activity ofthis enzyme in viva. This method can be used to determine the activity of the enzyme in tissues as well as the extent and