✦ LIBER ✦

Inhibition of CYP3A4 and CYP3A5 catalyzed metabolism of alprazolam and quinine by ketoconazole as racemate and four different enantiomers

✍ Scribed by Annika Allqvist; Jun Miura; Leif Bertilsson; Rajaa A. Mirghani

Book ID: 105921452
Publisher: Springer
Year: 2007
Tongue: English
Weight: 149 KB
Volume: 63
Category: Article
ISSN: 0031-6970
DOI: 10.1007/s00228-006-0230-z

No coin nor oath required. For personal study only.

📜 SIMILAR VOLUMES

In Vitro/in Vivo scaling of alprazolam m

In Vitro/in Vivo scaling of alprazolam metabolism by CYP3A4 and CYP3A5 in humans

✍ Noriko Hirota; Kiyomi Ito; Takafumi Iwatsubo; Carol E. Green; Charles A. Tyson; 📂 Article 📅 2001 🏛 John Wiley and Sons 🌐 English ⚖ 243 KB 👁 1 views

We attempted to predict the in vivo metabolic clearance of alprazolam from in vitro metabolic studies using human liver microsomes and human CYP recombinants. Good correlations were observed between the intrinsic clearance (CL int ) for 4-hydroxylation and CYP3A4 content and between the CL int for a

Enantioselectivity of inhibition of cyto

Enantioselectivity of inhibition of cytochrome P450 3A4 (CYP3A4) by ketoconazole: Testosterone and methadone as substrates

✍ Shahrzad Dilmaghanian; John G. Gerber; Scott G. Filler; Angela Sanchez; Joseph G 📂 Article 📅 2004 🏛 John Wiley and Sons 🌐 English ⚖ 143 KB 👁 1 views

Inhibition of Human CYP3A Catalyzed 1′-H

Inhibition of Human CYP3A Catalyzed 1′-Hydroxy Midazolam Formation by Ketoconazole, Nifedipine, Erythromycin, Cimetidine, and Nizatidine

✍ Steven A. Wrighton; Barbara J. Ring 📂 Article 📅 1994 🏛 Springer US 🌐 English ⚖ 661 KB