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Inhibition of CPP32 blocks surface IgM-mediated apoptosis and D4-GDI cleavage in human BL60 Burkitt lymphoma cells

✍ Scribed by Anke Rickers; Ekkehard Brockstedt; Markus Y. Mapara; Albrecht Otto; Bernd Dörken; Kurt Bommert

Publisher
John Wiley and Sons
Year
1998
Tongue
English
Weight
173 KB
Volume
28
Category
Article
ISSN
0014-2980

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## Abstract Major regulators of programmed cell death, or apoptosis, are the members of the bcl‐2 gene family. Recently, we reported that surface(s) IgM triggering of the human B lymphoma cell line BL‐41 led to strong induction of bax‐α, a death‐promoting member of the bcl‐2 family, and subsequentl